Watch Carefully (1)pentobarbital will reduce the level or outcome of buprenorphine subdermal implant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Keep an eye on sufferers presently on buprenorphine subdermal implant who need recently-initiated therapy with CYP3A4 inducer for signs and signs or symptoms o… Read More